Research
Research Interests
Coding DNA sequence (CDS) architecture <-> protein design
Evolutionary Systems Biology
Large-scale (Meta)genomics
Microbial symbionts
Microbial Metabolism (Methanotrophy)
Publications
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Dutkiewicz Z, Singleton CM, Sereika M, Villada JC, Mussig AJ, Chuvochina M, Albertsen M, Schulz F, Woyke T, Nielsen PH, Hugenholtz P (2024). Proposal of Patescibacterium danicum gen. Nov., sp. nov. in the ubiquitous ultrasmall bacterial phylum Patescibacteriota phyl. Nov. ISME Communications. Link - PDF
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Villada JC & Schulz F. (2022). The endosymbiotic box of protective tricks. Nature Reviews Microbiology. Link - PDF
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Villada JC, Duran MF, Lim CK, Stein LY & Lee PKH (2022). Integrative genome-Scale metabolic modeling reveals versatile metabolic strategies for methane utilization in Methylomicrobium album BG8. mSystems. Link - PDF
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Villada JC, Duran MF & Lee PKH (2020). Interplay between position-dependent codon usage bias and hydrogen bonding at the 5ʹ end of ORFeomes. mSystems. Link - PDF
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Villada JC, Duran MF & Lee PKH (2019). Genomic evidence for simultaneous optimization of transcription and translation through codon variants in the pmoCAB operon of type Ia methanotrophs. mSystems. Link - PDF
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Lim CK, Villada JC, Chalifour A, Duran MF, H Lu & Lee PKH (2019). Designing and engineering Methylorubrum extorquens AM1 for itaconic acid production. Frontiers in Microbiology. Link - PDF
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Lu H, Villada JC, & Lee PK (2018). Modular metabolic engineering for biobased chemical production. Trends in Biotechnology. Link - PDF
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Villada JC, Brustolini OJB, & da Silveira WB. (2017). Integrated analysis of individual codon contribution to protein biosynthesis reveals a new approach to improving the basis of rational gene design. DNA Research. Link - PDF
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Diniz RHS, Villada JC, Alvim MCT, Vidigal PMP, Vieira NM, Lamas-Maceiras M, … & da Silveira, WB (2017). Transcriptome analysis of the thermotolerant yeast Kluyveromyces marxianus CCT 7735 under ethanol stress. Applied Microbiology and Biotechnology. Link - PDF
Awards
(2018) Best of the Best Award – B4B Challenge Big Data for Business. Hong Kong Science & Technology Park (HKSTP). Hong Kong SAR
(2016) The Hong Kong PhD Fellowship. Hong Kong PhD Fellowship Scheme (HKPFS) of the Research Grants Council (RGC) of Hong Kong. Hong Kong SAR
(2016) The European Molecular Biology Laboratory (EMBL) Programme Fellowship. EMBL Corporate Partnership. The European Molecular Biology Laboratory (EMBL) Heidelberg, Germany
(2016) Chow Yei Ching School of Graduate Studies Entrance Scholarship. School of Graduate Studies - City University of Hong Kong. Hong Kong SAR
(2013) Organization of American States (OAS-GCUB) Scholarship. MSc studies in Brazil. Research on Bioinformatics for Biotechnology. Washington, DC. USA.
(2013) Laureate Award by The Faculty of Engineering Council. Award for Excellence of the BSc. Graduation Project in Bioinformatics for Agriculture Biotechnology. Cali, Colombia.
Education
PhD. Energy and Environment. (2021) City University of Hong Kong. Research: Genomics and Systems Biology of Aerobic Methanotrophs.
MSc. Agricultural Microbiology. (2016) Universidade Federal de Viçosa. Research: Individual Codon Contribution to Protein Biosynthesis in Yeast.
BSc. Agricultural Engineering. (2013) Universidad del Valle. Research: Comparative Genomics of Nitrogen Fixing Bacteria.